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Article considers the analysis of working conditions of conductors of cars. Major harmful and adverse production factors inherent in this profession: vibration, noise, dust content, chemicals, adverse microbiological atmosphere. Work of conductors belongs to category of «travelling» pro-fessions, and, bigger number of conductors are occupied on long trips, moving during 3 and more (till 7 days). The incidence structure also has a number of differences: at conductors of cars diseas-es of respiratory organs, bodies of blood circulation, bone and muscular system, a trauma and al-lergic diseases prevail. Diseases of respiratory system at conductors make more than a half of all cases of temporary disability and meet mainly in the form of ORZ, rhinitises, bronchitis and pneu-monia that indicates the need of regulation and normalization of the air environment of the car which is object of long stay and a conductor workplace.