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Within the framework of the article, a study was made of the workplace of wheelchair washers for the purpose of determining the main occupational diseases and the causes of their occurrence. The theory of constructing rational modes of work and rest for working in the off-season in the open air is considered. The equation of integral index of cooling conditions is given. The risks associated with working in the cold are listed, as well as basic protection measures for workers, such as personal protective equipment and recommendations for restroom equipment. Within the framework of the article, the technological stages of manual washing of passenger carriages and a number of harmful production factors at the workplace of wheelchair washers are considered. In the process of analyzing the working conditions of the profession in question, a number of prof. diseases such as acute intoxication, dermatitis and dermatosis. The results of the conducted tests for the evaluation of the toxicity index and operational tests of samples of the detergent «Trans-Eco» with the aim of improving the working conditions of the passenger car wipers are presented.