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This article provides an analysis of the failure of mechanical equipment freight electric loco-motive 2ES6 "Sinara". The aim is to analyze the main failure of the mechanical part, the causes of failure . Using statistical methods for estimating and accounting data form TU -29 "Book of dam-age or malfunction of locomotives and multiple units and their equipment" locomotive repair depot «Мoskovka» investigated. Mechanical equipment failures make up 8.72% of all failures locomotive. Mean operating time to failure of the mechanical part locomotive is L2=156221km. Failure analy-sis of mechanical equipment showed that about 50% of all faults related to the deterioration of the rolling surface of the wheelset . More than a third of all failures associated with unilateral wheel flange wear. Mean time to failure due to a unilateral wheelset wear bandage is L1=279874 km. One reason is the incorrect distribution the load on the wheelsets at the factory and in the process of the attendance, maintenance. About 20% of mechanical equipment failures account for the fail-ure ventilation pipes. Analysis showed that the problem appears in the winter season. The main reason is a design defect ventilation pipes. Other types of mechanical equipment failures have less statistical significance. For comparison, the paper analyzes the distribution of electric locomotives VL10 mechanical failures. The obtained dependences can be a source of information for the system repair locomotives 2ES6 "Sinara" on-condition maintenance.